Antimicrobial action and cytotoxicity of hypochlorous acid obtained from an innovative electrolytic device - An in vitro study.

OBJECTIVE: This study evaluated the antimicrobial effect and cytotoxicity of hypochlorous acid(HClO) obtained from an innovative electrolytic device. DESIGN: The root canals of fifty extracted human teeth were inoculated with Enterococcus faecalis and divided into 5 groups (n = 10): DW (control); 2% chlorhexidine gel(CHX); 2.5% sodium hypochlorite(NaOCl); 250 ppm HClO and 500 ppm HClO. The counting of colony forming units evaluated the decontamination potential of each group. Cytotoxicity was evaluated after inoculation of tested protocols in fibroblastic cells for 3 min, calculating the cell viability. Specific statistical analysis was performed (α = 5%). RESULTS: The highest bacterial reduction was observed in experimental groups, with no statistical differences from each other (p > 0.05). The highest number of viable cells was observed in control group, followed by 250 ppm HClO and 500 ppm HClO groups, with statistical differences from each other (p < 0.05). CONCLUSIONS: It could be concluded that HClO presented high antimicrobial activity and low cytotoxicity at both tested concentrations.

Choosing Juvéderm Volux™ to chin augmentation: Case report and flowchart for clinical evaluation.

INTRODUCTION: The development of filler biomaterials with high hyaluronic acid concentrations, cohesiveness, and elastic modulus has become an option for chin augmentation, as the balance of these rheological properties promotes high lifting capacity, providing minimally invasive perceptible improvements in patient appearance. PRESENTATION OF CASE: The present study reviewed clinical and anatomical aspects of patients referred for chin augmentation and created a flowchart to assertively diagnose patients with an indication of Juvéderm® Volux™ for defining the lower third of the face. DISCUSSION: The chin is vital for facial proportions and attractiveness perception. Its relevance to facial appearance is noticed the most when chin size is less than ideal, making other facial areas seem larger or smaller. The adjacent soft tissues of the neck and jaw appear prematurely aged when chin projection or width is inadequate. Hyaluronic acid-based fillers have a confirmed history of safe and effective use for treating facial volume loss or deficiency. CONCLUSION: Juvéderm® Volux™ is a safe, effective, and long-lasting alternative for restoring and creating facial volume and sculpting, shaping, and contouring the chin and jaw.

Maxillofacial infections of dental origin: risk factors for hospital admission

Aim: to evaluate the occurrence of maxillofacial infection cases, which were treated at local hospital, identifying the main risk factors that determine the need for hospitalization of patients and the factors associated with staying length. Methods: A retrospective review of 191 records of patients with maxillofacial infection of odontogenic origin was performed, statistically evaluated by frequency and percentage of involvement, p values (based on the chi-square test) and odds ratio with a 95% confidence interval. A p-value <0.05 was considered statistically significant. Results: Among all the 191 patients, 31 had some harmful habits, such as smokers (13%) and alcoholics (1%). In addition, 39 patients reported some general health problem, such as systemic arterial hypertension (8.3%), depression (6.8%), diabetes (3.6%) and some immunosuppression (1.57%). Involvement of infection in deep facial spaces was present, with 119 patients presenting a deeper infection (62.3%) and 72 patients a superficial infection (37.7%). The most prevalent clinical signs and symptoms in the initial evaluation were pain (91.1%) and edema (90.1%), followed by erythema/hyperemia (44.5%), trismus (37.7%), abscess (30.9%), cellulitis (27.7%), f istula (16.8%), fever (16.8%), dysphagia (11%), dehydration (9.9%), odynophagia (7.9% ) and dyspnea (3.7%). Pulp necrosis was considered a risk factor for treatment in a hospital environment (0.032) and root canal treatment decreases the risk of hospitalization (p=0.002). Considering the evaluated patients, 146 (76.4%) were admitted and 45 (37.7%) were not admitted for hospitalization after initial clinical evaluation. Conclusion: there is a high occurrence of maxillofacial infection cases of dental origin, considering that involvement of infection in deeper facial spaces, as well as presence of pain, edema, erythema/hyperemia, trismus, abscess, cellulitis and pulp necrosis, represent the main risk factors for hospitalization and staying length

Volumetric Evaluation of the Upper Airways in Relation to the Gonial Angle / Avaliação Volumétrica das Vias Aéreas Superiores com Relação ao Ângulo Goníaco

The upper airspace is essential to understand the physiology and pathogenesis of its obstruction, complementary exams based on images have been used to evaluate the upper airspace. The objective of this study was to evaluate, by means of computed tomography, the upper airways (UAS), in relation to anatomical variables, emphasizing the gonial angle and comparing it with volume in mm³, sex and age. A total of 124 computed tomography scans were analyzed using DICOM files (digital image communication in medicine) made available by a radiology clinic using the ITK-snap program (version 3.6.0), upper airway volumes, sex, age and gonial angle values on both the right and left sides were tabulated in a table in the Excel 2010 program of the Microsoft Office 2010 package, and subsequently analyzed in the SPSS software with statistical analysis using the Levene Test and also the ANOVA test, to obtain of the results. The values found for the gonial angle did not indicate a significant difference. However, the present work confirms that within each of these groups there is a homogeneity of variances, corroborating the results reported in the literature. However, regarding the volume of the upper airways, we found that in men and in individuals aged over 34 years, the volume is greater.(AU)

O espaço aéreo superior é essencial para compreender a fisiologia e a patogênese de sua obstrução, exames complementares baseados em imagens têm sido empregados para avaliar o espaço aéreo superior. O objetivo desse estudo foi avaliar por meio de tomografia computadorizada, as vias aéreas superiores (VAS), com relação a variáveis anatômicas, dando ênfase ao ângulo goníaco e comparando com volume em mm³, sexo e idade. Foram analisados 124 exames de tomográfica computadorizada, por meio dos arquivos DICOM (comunicação de imagens digitais em medicina) disponibilizados por uma clínica radiológica, através do programa ITK-snap (versão 3.6.0), os volumes das vias aéreas superiores, o sexo, a idade e os valores do ângulo goníaco tanto do lado direito como do lado esquerdo foram tabulados em tabela no programa Excel 2010 do pacote Microsoft Office 2010, e analisados posteriormente no software SPSS com análise estatística pelo Teste de Levene e também teste ANOVA, para obtenção dos resultados. Os valores encontrados para o ângulo goníaco não indicaram diferença significativa. Contudo, o presente trabalho confirma que dentro de cada um desses grupos há uma homogeneidade das variâncias e corroborando com os resultados relatados na literatura. No entanto com relação ao volume das vias aéreas superiores encontramos que em homens e em indivíduos com idade superior a 34 anos o volume é superior.(AU)

Defeito ósseo de Stafne uma depressão lingual na mandíbula: revisão da literatura / Stafne's bone defect a lingual depression in the jaw: literature review

O defeito ósseo de Stafne foi considerado por muito tempo como um cisto ósseo por se apresentar radiograficamente de forma radiolúcida, circunscrita, com bordas delimitadas e em quase todos os casos unilateral. Hoje em dia já se sabe que é uma depressão e/ou cavidade óssea causada pelo alojamento da glândula submandibular ou parte dela e/ou seus tecidos adjacentes na região posterior da mandíbula, ou na região anterior em casos mais raros pelo alojamento da glândula sublingual. Sendo assim, o objetivo deste trabalho é realizar uma breve revisão da literatura acerca das características mais frequentes e suas variações desta anomalia anatômica. As buscas foram realizas em periódicos de artigos científicos publicado nas bases de dados eletrônicas: PubMed, Scielo e Google Acadêmico, contendo artigos científicos dos últimos dez anos nos idiomas inglês e português. Os dados mostram que o defeito ósseo de stafne tem predileção pelo sexo masculino, é assintomática, pois se trata de uma alteração anatômica, não requer tratamento, portanto cabe ao cirurgião dentista ter conhecimento, uma vez que este é encontrado de forma ocasional em radiografias panorâmicas para investigação de outras circunstancias, e que muitas vezes acaba levando o profissional odontólogo a realizar diagnósticos errôneos ou exames mutiladores como a biopsia que são desnecessários nesta situação pelo fato desta variação anatômica ter características muitos semelhantes aos cistos.

Stafne's bone defect was considered for a long time as a bone cyst because it presents radiographically in a radiolucent, circumscribed form, with delimited borders and, in almost all cases, unilateral. Nowadays it is known that it is a depression and / or bone cavity caused by the accommodation of the submandibular gland or part of it and / or its adjacent tissues in the posterior region of the mandible, or in the anterior region in rarer cases by the accommodation of the sublingual gland. Therefore, the objective of this work is to carry out a brief literature review of the more specific characteristics and their variations of this anatomical anomaly. Searches were performed in journals of scientific articles published in electronic databases: PubMed, Scielo and Academic Google, containing scientific articles from the last ten years in English and Portuguese. The data show that the stafne bone defect has a predilection for males, it is asymptomatic, as it is an anatomical alteration, does not require treatment, therefore it is up to the dental surgeon to be aware, once panoramic to investigate other circumstances, and that many Sometimes it ends up leading the dental professional to perform misdiagnosis or mutilating tests such as a biopsy, which are unnecessary in this situation because this anatomical variation has characteristics that are very similar to cysts.

Effectiveness of ultrasonic activation over glycolic acid on microhardness, cohesive strength, flexural strength, and fracture resistance of the root dentin.

OBJECTIVES: The aim of this study was to evaluate the effectiveness of ultrasonic activation (US) over glycolic acid on microhardness, cohesive strength, flexural strength, and fracture resistance of root dentin, comparing with conventional final irrigation protocols. METHODS: Samples were obtained from 140 extracted bovine teeth and distributed into four test groups: microhardness (50 teeth), cohesive strength (15 teeth), flexural strength (15 teeth), and fracture resistance (60 teeth). In all four tests, specimens were subdivided into five groups, according to final irrigation protocols: G1: distilled water (DW); G2: 17% ethylenediaminetetraacetic acid (EDTA); G3: 17% glycolic acid (GA); G4: 17% EDTA + US; and G5: 17% GA + US. The duration time of each protocol was set in 1 min. After irrigation protocols, the Vickers tester was used to evaluate microhardness and the universal testing machine was used to evaluate the cohesive strength, flexural strength, and fracture resistance of the root dentin. One-way ANOVA test and the Tukey HSD were used for multiple comparison tests in all evaluations (α = 5%). RESULTS: In general, groups 2 (EDTA), 4 (EDTA + US), and 5 (GA + US) promoted the highest reduction of microhardness, being statistically different from other groups (p < 0.05). Cohesive strength, flexural strength, and fracture resistance data revealed that no differences between groups were observed (p > 0.05). CONCLUSIONS: The association of GA and US results in microhardness reduction, with no influence on cohesive strength, flexural strength, and fracture resistance of the root dentin. CLINICAL RELEVANCE: The use of US over GA has no influence on some mechanical properties of root dentin.